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CONTRACTED MANUFACTURE

受託製造

CHEMICALS

Equipment for special reactions

Super low-temperature reaction

Transformation of carboxylic acid derivation to aldehyde via Weinreb amide

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Corey-Fuchs alkyne synthesis

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1000 L super low temperature reaction reactor

Low-pressure hydrogenation reaction

Catalytic hydrogenation reaction by using a metal catalyst

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1200 L low-pressure hydrogenation reaction reactor

Safe scale-up of borane reduction

Implementation example 1 : Using 6000 L

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Implementation example 2 : Using 9000 L

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Characteristics of generated diborane gas

・Risk of spontaneous combustion and explosion
・Toxicity level hazardous to human health

Production scale can be increased through quenching and controlling diborane gas generation

Fluorine corrosion resistant equipment

Reactions using various fluorinating agents are possible

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Capable of handling processes with risk of GL corrosion due to hydrofluoric acid generation

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Although separation of a CF3 group is not easy, fluoride ion may be eliminated when an electron donating group exists via an aromatic ring.

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GMP compliant 2,000 L fluororesin lined reactor (with carbon condenser)